Surgery on lymph system has become an important long-term treatment of lymphedema. The performance of this demanding surgical procedure is increasing all over the world. In order to be able to assess the situation of the lymphedema and to decide on the lymph surgery an assessment of the lymphatics is necessary. The fluorescence angiography allows you to visualize the functionality, individual physiology, velocity of the lymphatics and thus severity of a lymphedema. Having the real-time picture of the patient’s lymphatics surgeon can decide on the best suitable surgical procedure. This presentation will show the use of fluorescence lymphangiography and different surgical procedures on lymphedema treatment.